The department is headed by a director responsible to undertake any assigned role by the Honourable Commissioner for Health.
There are also six agencies/parastatals under the Ministry, namely;
- Hospital Management Board (HMB)
- Primary Health Care Management Board (PHCMB)
- Drugs & Medical Consumables Supply Agency (DMCSA)
- State Agency for the Control of AIDS (SACA)
- Kano State Contributory Health care Management Agency (KSCHMA)
- Private Health Institutions Management Agency (PHIMA)